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2nd Singapore Structural Biology Symposium 2024

29 February 2024

Duke-NUS Amphitheatre, Level 2
8 College Road, Singapore 169857

The 2nd Singapore Structural Biology Symposium (SSBS) is a vibrant symposium and networking platform to showcase and focus on advanced, cutting-edge research in the field of macromolecular X-ray crystallography, cryo-electron microscopy, nuclear magnetic resonance (NMR) as well as other structural biology techniques. The symposium will feature leading local structural biologists and young, aspiring researchers.

The symposium will be held on the 29th of February 2024, at Duke-NUS Amphitheatre. Registration for participation is open and FREE to all local institution staff and students. The registration period is now open till 19 January 2024. For enquiries, contact us at sg.structure.bio@gmail.com

16

Speakers

~100

Attendees

1

Day

Registration is now closed

1 Day

16 Speakers

SSBS 2024

29/02/2024

Programme

Captivating keynote addresses, insightful panel discussions, and interactive workshops, elucidating the latest advancements in deciphering molecular structures and their implications in drug design, disease mechanisms, and biomolecular interactions.

Plenary Speakers

Richard Gerald Brennan

Richard Gerald Brennan

James B. Duke Distinguished
Professor of Biochemistry
Chair, Department of Biochemistry
Duke University, USA

Filippo Mancia

Filippo Mancia

Professor of Physiology & Cellular Biophysics
Co-Director of Graduate Studies, Department Physiology & Cellular Biophysics
Columbia University, USA

Yifan Cheng

Yifan Cheng

Professor, Biochemistry and Biophysics, School of Medicine
HHMI Investigator
University of California San Francisco, USA

Speakers

Alain Ange Marie Filloux

Director, Singapore Centre for Environmental Life Sciences Engineering (SCELSE)
Professor
NTU, Singapore

Mok Yu-keung Henry

Mok Yu-keung Henry

Associate Professor
Deputy Head of Department
NUS, Singapore

Phan Anh Tuan

Phan Anh Tuan

Chair, School of Physical & Mathematical Sciences
Professor
NTU, Singapore

Tristan Bepler

Tristan Bepler

Group Leader
Simons Machine Learning Centre, USA

Co-founder and CEO
NE47, Singapore

Xiao Tianshu

Xiao Tianshu

Assistant Professor
NTU, Singapore

Qu Kun

Qu Kun

Assistant Professor
NUS, Singapore

Xiao Tianshu

Hu Chunyi

Assistant Professor
NUS, Singapore

igor N Berezovosky

Igor N Berezovsky

Senior Principal Investigator
A*STAR, Singapore

Lin Zhewang

Lin Zhewang

Assistant Professor
NUS, Singapore

Peter J Bond

Peter J Bond

Senior Principal Investigator
A*STAR, Singapore

igor N Berezovosky

Alexander Ludwig

Assistant Professor
NTU, Singapore

Tan Yaw Sing

Tan Yaw Sing

Assistant Principal Investigator
A*STAR, Singapore

Peter J Bond

Yang Zhang

Professor
NUS, Singapore

SCHEDULE

8:00 AM Registration
8:30 AM Opening address (Yu Hao, NUS)
8:40 AM Welcome address (Shee-Mei Lok, Duke-NUS)
Morning Session 
Session Chair  Jayaraman Sivaraman, NUS
8:45 AM Plenary speaker (Richard Brennan, Duke USA)
MtrR on Steroids
9:15 AM Alain Filloux, NTU
Structural insights on loading the T6SS bacterial gun with toxic bullets
9:35 AM Henry Mok, NUS
Scaffold stability of the Kazal-type inhibitor AaTI and how Dengue virus capture human plasmin for infection of mosquito
9:55 AM Phan Anh Tuan, NTU
Structural basis for G-quadruplex recognition by proteins
10:15 AM Plenary speaker (Filippo Mancia, Columbia University USA)
Structural Basis of Lipopolysaccharide maturation by the O-antigen ligase
10:45 AM Coffee break (20 minutes)
Session Chair  Liew Chong Wai, NTU
11:05 AM Thermo Fisher Scientific
11:20 AM Cytiva
11:35 AM GenScript
11:50 AM Photo taking
12:00 PM Lunch (1 hour 30 minutes)
Afternoon Session 
Session Chair Tan Yong Zi, NUS
1:30 PM Tristan Bepler, NE47 & SMLC USA
Fast and accurate annotation of filaments and membranes in micrographs and tomograms with TARDIS
1:50 PM Xiao Tianshu, NTU
Structure- and function-based antiviral therapeutic development
2:10 PM Qu Kun, NUS
Membrane dynamics during virus maturation and vesicle formation
2:30 PM Peter Bond, A*STAR
Host Recognition of SARS-CoV-2 Spike: A Double-Edged Sword
2:50 PM Chunyi Hu, NUS
Decoding the Activation and Inactivation Mechanisms of Type I-C CRISPR-Cas3 system
3:10pm Igor Berzovsky, A*STAR
Allostery: from molecular mechanisms to biomedical implications
3:30 PM Tea break (30 minutes)
 
Session Chair Shee-Mei Lok, Duke-NUS
4:00 PM Zhewang Lin, NUS
Mechanism of Tubulin Autoregulation: Marking the Ribosome for Targeted mRNA Control
4:20 PM Alexander Ludwig, NTU
Native architecture of the human Barr Body studied by correlative light and cryo electron tomography
4:40 PM Tan Yaw Sing, A*STAR
Unveiling the secret pockets of proteins for drug discovery
5:00 PM Yang Zhang, NUS
Towards the solution of the protein structure prediction problem
5:20 PM Plenary Speaker (Yifan Cheng, UCSF USA)
Structures of INO80-hex and -nuc complexes
5:50 PM Closing address (Liou Yih-Cherng, NUS)

Location and Date

 

Address

Duke-NUS Medical School
8 College Rd Singapore 169857

 Date
29th February 2024

Contact

 

Secretariat
Singapore Structural Biology Symposium
sg.structure.bio@gmail.com

Organised by

NUS
NUS

Platinum Sponsor

Thermo-Fisher Scientific

Gold Sponsors

cytiva
GenScript

Silver Sponsor

Sartorius

Organising Committee

LOK, Sheemei | Duke-NUS, Singapore (Chair)
SIVARAMAN, Jayaraman | NUS, Singapore
LESCAR, Julien | NTU, Singapore
LIOU, Yih-Cherng| NUS, Singapore
TAN, Yong Zi | NUS, Singapore
LIEW, Chong Wai | NTU, Singapore